cd68 (Cell Signaling Technology Inc)
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Cd68, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 97/100, based on 361 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cd68/CD68+Rabbit+mAb/pm42892644-152-5-8
Average 97 stars, based on 361 article reviews
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Blocking Assay:Article Title: RNF144B deficiency aggravated neuroinflammatory response induced by cerebral ischemic stroke via regulating TRAF3 ubiquitination. Article Snippet: Stroke, as a predominant cerebrovascular event, is characterized by disproportionately high morbidity, disability, and mortality rates.. The central role of neuroinflammation in its pathophysiology underscores the clinical significance of modulating related regulatory pathways.. Notably, ring finger protein 144B (RNF144B), an E3 ubiquitin ligase with demonstrated anti-inflammatory properties, presents a potential novel therapeutic target. Incubation:Article Title: RNF144B deficiency aggravated neuroinflammatory response induced by cerebral ischemic stroke via regulating TRAF3 ubiquitination. Article Snippet: Stroke, as a predominant cerebrovascular event, is characterized by disproportionately high morbidity, disability, and mortality rates.. The central role of neuroinflammation in its pathophysiology underscores the clinical significance of modulating related regulatory pathways.. Notably, ring finger protein 144B (RNF144B), an E3 ubiquitin ligase with demonstrated anti-inflammatory properties, presents a potential novel therapeutic target. Article Title: Effect of Diosmetin on Gut Microbiota and Serum Metabolites in Acute Pancreatitis Mice: A Metagenomic and Metabolomic Study Article Snippet: Diosmetin is a bioactive flavonoid that exhibits welldocumented antioxidant, antiinflammatory, and antitumor properties.. However, its potential to attenuate acute pancreatitis (AP) progression through gut microbiota modulation has not yet been elucidated.. In this study, mice were pretreated with varying oral doses of diosmetin for 1 week before AP induction via intraperitoneal (i.p.) caerulein injections. Article Title: A Novel Plasma Biomarker hsa_circ_0080018 Drives DLBCL Progression via M2 Polarization of Tumor-Associated Macrophages. Article Snippet: .. Tissue sections were incubated with Article Title: Single-Cell RNA Sequencing deciphers the imbalance of Microenvironment of the Maternal-Fetal Interface in Cesarean Scar Pregnancy. Article Snippet: Cesarean scar pregnancy (CSP) has posed a serious threat to women’s reproductive health.. The view on its mechanism remained controversial.. Here, we performed a single-cell sequencing on villi and decidua from three normal and three cesarean scar pregnancies in patients with a histor y of cesarean deliver y. Enrichment analysis was performed to elucidate the functional roles of various cell t ypes. Immunohistochemistry:Article Title: Donor-derived CD8 + CD122 + Tregs generated in mixed donor chimeric NOD mice delete autoreactive T cells Article Snippet: .. The following antibodies were used for immunohistochemistry analysis: anti-CD3 (Cell Signaling, clone D7A6E, dilution 1:200) and Cell-Signaling:Article Title: Ephedrae Herba and Armeniacae Semen Amarum combination alleviates LPS-induced acute lung injury by targeting the TLR4/NF-κB and NLRP3 pathways. Article Snippet: ALI is a severe clinical syndrome with limited treatment options beyond corticosteroids, which cause significant adverse effects.. This study demonstrates that the herbal combination EAC significantly attenuates LPS-induced ALI through dual pathway inhibition.. EAC suppresses TLR4/NF-κB and NLRP3 inflammasome signaling, thereby inhibiting MyD88-mediated NF-κB activation, NLRP3 inflammasome assembly, caspase-1 activation, and GSDMD|mediated pyroptosis. Magnetic Resonance Imaging:Article Title: Ephedrae Herba and Armeniacae Semen Amarum combination alleviates LPS-induced acute lung injury by targeting the TLR4/NF-κB and NLRP3 pathways. Article Snippet: ALI is a severe clinical syndrome with limited treatment options beyond corticosteroids, which cause significant adverse effects.. This study demonstrates that the herbal combination EAC significantly attenuates LPS-induced ALI through dual pathway inhibition.. EAC suppresses TLR4/NF-κB and NLRP3 inflammasome signaling, thereby inhibiting MyD88-mediated NF-κB activation, NLRP3 inflammasome assembly, caspase-1 activation, and GSDMD|mediated pyroptosis. Multiplex Assay:Article Title: IL1β + macrophages promote intestinal fibrosis in Crohn's disease by secreting AREG to activate PI16 + fibroblasts. Article Snippet: Slides were enclosed using nail polish, scanned using the SLIDEVIEW VS200 (Olympus), and analyzed with HALO software. .. The following antibodies and corresponding fluorescent dyes were used for multiplex immunofluorescence staining: PI16 (1:100, 12267-1-AP, Proteintech); IL1β (CST, #12703, 1:200); Immunofluorescence:Article Title: IL1β + macrophages promote intestinal fibrosis in Crohn's disease by secreting AREG to activate PI16 + fibroblasts. Article Snippet: Slides were enclosed using nail polish, scanned using the SLIDEVIEW VS200 (Olympus), and analyzed with HALO software. .. The following antibodies and corresponding fluorescent dyes were used for multiplex immunofluorescence staining: PI16 (1:100, 12267-1-AP, Proteintech); IL1β (CST, #12703, 1:200); Staining:Article Title: IL1β + macrophages promote intestinal fibrosis in Crohn's disease by secreting AREG to activate PI16 + fibroblasts. Article Snippet: Slides were enclosed using nail polish, scanned using the SLIDEVIEW VS200 (Olympus), and analyzed with HALO software. .. The following antibodies and corresponding fluorescent dyes were used for multiplex immunofluorescence staining: PI16 (1:100, 12267-1-AP, Proteintech); IL1β (CST, #12703, 1:200); Article Title: Effect of Diosmetin on Gut Microbiota and Serum Metabolites in Acute Pancreatitis Mice: A Metagenomic and Metabolomic Study Article Snippet: Diosmetin is a bioactive flavonoid that exhibits welldocumented antioxidant, antiinflammatory, and antitumor properties.. However, its potential to attenuate acute pancreatitis (AP) progression through gut microbiota modulation has not yet been elucidated.. In this study, mice were pretreated with varying oral doses of diosmetin for 1 week before AP induction via intraperitoneal (i.p.) caerulein injections. Tissue:Article Title: A Novel Plasma Biomarker hsa_circ_0080018 Drives DLBCL Progression via M2 Polarization of Tumor-Associated Macrophages. Article Snippet: .. Tissue sections were incubated with Immune Cell:Article Title: Single-Cell RNA Sequencing deciphers the imbalance of Microenvironment of the Maternal-Fetal Interface in Cesarean Scar Pregnancy. Article Snippet: Cesarean scar pregnancy (CSP) has posed a serious threat to women’s reproductive health.. The view on its mechanism remained controversial.. Here, we performed a single-cell sequencing on villi and decidua from three normal and three cesarean scar pregnancies in patients with a histor y of cesarean deliver y. Enrichment analysis was performed to elucidate the functional roles of various cell t ypes. |
