Review



cd68  (Cell Signaling Technology Inc)


Bioz Verified Symbol Cell Signaling Technology Inc is a verified supplier
Bioz Manufacturer Symbol Cell Signaling Technology Inc manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 97

    Structured Review

    Cell Signaling Technology Inc cd68
    Cd68, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 97/100, based on 361 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/cd68/CD68+Rabbit+mAb/pm42892644-152-5-8
    Average 97 stars, based on 361 article reviews
    cd68 - by Bioz Stars, 2026-10
    97/100 stars

    Images

    Related Articles

    Blocking Assay:

    Article Title: RNF144B deficiency aggravated neuroinflammatory response induced by cerebral ischemic stroke via regulating TRAF3 ubiquitination.
    Article Snippet: Stroke, as a predominant cerebrovascular event, is characterized by disproportionately high morbidity, disability, and mortality rates.. The central role of neuroinflammation in its pathophysiology underscores the clinical significance of modulating related regulatory pathways.. Notably, ring finger protein 144B (RNF144B), an E3 ubiquitin ligase with demonstrated anti-inflammatory properties, presents a potential novel therapeutic target.

    Incubation:

    Article Title: RNF144B deficiency aggravated neuroinflammatory response induced by cerebral ischemic stroke via regulating TRAF3 ubiquitination.
    Article Snippet: Stroke, as a predominant cerebrovascular event, is characterized by disproportionately high morbidity, disability, and mortality rates.. The central role of neuroinflammation in its pathophysiology underscores the clinical significance of modulating related regulatory pathways.. Notably, ring finger protein 144B (RNF144B), an E3 ubiquitin ligase with demonstrated anti-inflammatory properties, presents a potential novel therapeutic target.

    Article Title: Effect of Diosmetin on Gut Microbiota and Serum Metabolites in Acute Pancreatitis Mice: A Metagenomic and Metabolomic Study
    Article Snippet: Diosmetin is a bioactive flavonoid that exhibits welldocumented antioxidant, antiinflammatory, and antitumor properties.. However, its potential to attenuate acute pancreatitis (AP) progression through gut microbiota modulation has not yet been elucidated.. In this study, mice were pretreated with varying oral doses of diosmetin for 1 week before AP induction via intraperitoneal (i.p.) caerulein injections.

    Article Title: A Novel Plasma Biomarker hsa_circ_0080018 Drives DLBCL Progression via M2 Polarization of Tumor-Associated Macrophages.
    Article Snippet: .. Tissue sections were incubated with CD68 (#97778, CST), CD86 (#91882, CST), and CD163 (##93498, CST) antibodies at 4°C overnight and then incubated with biotinylated anti- rabbit secondary antibody for 2 h. Dako EnVision+ System- HRP (DAB) kits (Dako North America, USA) were used for signal development in the tissue sections. ..

    Article Title: Single-Cell RNA Sequencing deciphers the imbalance of Microenvironment of the Maternal-Fetal Interface in Cesarean Scar Pregnancy.
    Article Snippet: Cesarean scar pregnancy (CSP) has posed a serious threat to women’s reproductive health.. The view on its mechanism remained controversial.. Here, we performed a single-cell sequencing on villi and decidua from three normal and three cesarean scar pregnancies in patients with a histor y of cesarean deliver y. Enrichment analysis was performed to elucidate the functional roles of various cell t ypes.

    Immunohistochemistry:

    Article Title: Donor-derived CD8 + CD122 + Tregs generated in mixed donor chimeric NOD mice delete autoreactive T cells
    Article Snippet: .. The following antibodies were used for immunohistochemistry analysis: anti-CD3 (Cell Signaling, clone D7A6E, dilution 1:200) and CD68 (Cell Signaling, clone E3O7V, dilution 1:150). .. Total RNA was isolated using a NucleoSpin RNA Kit (Ref: 740955.50) and quantified using a Qubit Fluorometer (Invitrogen) and TapeStation 4200 (Agilent Technologies) for quality assessment.

    Cell-Signaling:

    Article Title: Ephedrae Herba and Armeniacae Semen Amarum combination alleviates LPS-induced acute lung injury by targeting the TLR4/NF-κB and NLRP3 pathways.
    Article Snippet: ALI is a severe clinical syndrome with limited treatment options beyond corticosteroids, which cause significant adverse effects.. This study demonstrates that the herbal combination EAC significantly attenuates LPS-induced ALI through dual pathway inhibition.. EAC suppresses TLR4/NF-κB and NLRP3 inflammasome signaling, thereby inhibiting MyD88-mediated NF-κB activation, NLRP3 inflammasome assembly, caspase-1 activation, and GSDMD|mediated pyroptosis.

    Magnetic Resonance Imaging:

    Article Title: Ephedrae Herba and Armeniacae Semen Amarum combination alleviates LPS-induced acute lung injury by targeting the TLR4/NF-κB and NLRP3 pathways.
    Article Snippet: ALI is a severe clinical syndrome with limited treatment options beyond corticosteroids, which cause significant adverse effects.. This study demonstrates that the herbal combination EAC significantly attenuates LPS-induced ALI through dual pathway inhibition.. EAC suppresses TLR4/NF-κB and NLRP3 inflammasome signaling, thereby inhibiting MyD88-mediated NF-κB activation, NLRP3 inflammasome assembly, caspase-1 activation, and GSDMD|mediated pyroptosis.

    Multiplex Assay:

    Article Title: IL1β + macrophages promote intestinal fibrosis in Crohn's disease by secreting AREG to activate PI16 + fibroblasts.
    Article Snippet: Slides were enclosed using nail polish, scanned using the SLIDEVIEW VS200 (Olympus), and analyzed with HALO software. .. The following antibodies and corresponding fluorescent dyes were used for multiplex immunofluorescence staining: PI16 (1:100, 12267-1-AP, Proteintech); IL1β (CST, #12703, 1:200); CD68 (CST, #97778, 1:200); anti-COL1A1 (1:100, #GB11022-100, Servicebio). ..

    Immunofluorescence:

    Article Title: IL1β + macrophages promote intestinal fibrosis in Crohn's disease by secreting AREG to activate PI16 + fibroblasts.
    Article Snippet: Slides were enclosed using nail polish, scanned using the SLIDEVIEW VS200 (Olympus), and analyzed with HALO software. .. The following antibodies and corresponding fluorescent dyes were used for multiplex immunofluorescence staining: PI16 (1:100, 12267-1-AP, Proteintech); IL1β (CST, #12703, 1:200); CD68 (CST, #97778, 1:200); anti-COL1A1 (1:100, #GB11022-100, Servicebio). ..

    Staining:

    Article Title: IL1β + macrophages promote intestinal fibrosis in Crohn's disease by secreting AREG to activate PI16 + fibroblasts.
    Article Snippet: Slides were enclosed using nail polish, scanned using the SLIDEVIEW VS200 (Olympus), and analyzed with HALO software. .. The following antibodies and corresponding fluorescent dyes were used for multiplex immunofluorescence staining: PI16 (1:100, 12267-1-AP, Proteintech); IL1β (CST, #12703, 1:200); CD68 (CST, #97778, 1:200); anti-COL1A1 (1:100, #GB11022-100, Servicebio). ..

    Article Title: Effect of Diosmetin on Gut Microbiota and Serum Metabolites in Acute Pancreatitis Mice: A Metagenomic and Metabolomic Study
    Article Snippet: Diosmetin is a bioactive flavonoid that exhibits welldocumented antioxidant, antiinflammatory, and antitumor properties.. However, its potential to attenuate acute pancreatitis (AP) progression through gut microbiota modulation has not yet been elucidated.. In this study, mice were pretreated with varying oral doses of diosmetin for 1 week before AP induction via intraperitoneal (i.p.) caerulein injections.

    Tissue:

    Article Title: A Novel Plasma Biomarker hsa_circ_0080018 Drives DLBCL Progression via M2 Polarization of Tumor-Associated Macrophages.
    Article Snippet: .. Tissue sections were incubated with CD68 (#97778, CST), CD86 (#91882, CST), and CD163 (##93498, CST) antibodies at 4°C overnight and then incubated with biotinylated anti- rabbit secondary antibody for 2 h. Dako EnVision+ System- HRP (DAB) kits (Dako North America, USA) were used for signal development in the tissue sections. ..

    Immune Cell:

    Article Title: Single-Cell RNA Sequencing deciphers the imbalance of Microenvironment of the Maternal-Fetal Interface in Cesarean Scar Pregnancy.
    Article Snippet: Cesarean scar pregnancy (CSP) has posed a serious threat to women’s reproductive health.. The view on its mechanism remained controversial.. Here, we performed a single-cell sequencing on villi and decidua from three normal and three cesarean scar pregnancies in patients with a histor y of cesarean deliver y. Enrichment analysis was performed to elucidate the functional roles of various cell t ypes.



    Similar Products

    86
    Arigo Biolaboratories mouse anti cd68
    Mouse Anti Cd68, supplied by Arigo Biolaboratories, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/cd68/anti+cd68+mouse/pmc13273865-449-6-13
    Average 86 stars, based on 1 article reviews
    mouse anti cd68 - by Bioz Stars, 2026-10
    86/100 stars
      Buy from Supplier

    95
    Novus Biologicals anti cd68
    Anti Cd68, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/cd68/CD68%2FSR-D1+Antibody+(KP1)+-+BSA+Free/pm42898474-263-13-15
    Average 95 stars, based on 1 article reviews
    anti cd68 - by Bioz Stars, 2026-10
    95/100 stars
      Buy from Supplier

    97
    Cell Signaling Technology Inc cd68
    Cd68, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/cd68/CD68+Rabbit+mAb/pm42892644-152-5-8
    Average 97 stars, based on 1 article reviews
    cd68 - by Bioz Stars, 2026-10
    97/100 stars
      Buy from Supplier

    96
    Bio-Rad differentiation 68
    Differentiation 68, supplied by Bio-Rad, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/cd68/Rat+anti+Mouse+CD68/pm42884680-117-52-57
    Average 96 stars, based on 1 article reviews
    differentiation 68 - by Bioz Stars, 2026-10
    96/100 stars
      Buy from Supplier

    96
    Bio-Rad cd68
    Cd68, supplied by Bio-Rad, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/cd68/Rat+anti+Mouse+CD68/pm42881225-532-20-21
    Average 96 stars, based on 1 article reviews
    cd68 - by Bioz Stars, 2026-10
    96/100 stars
      Buy from Supplier

    96
    Bio-Rad presynaptic structure
    Presynaptic Structure, supplied by Bio-Rad, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/cd68/Rat+anti+Mouse+CD68/pm42874698-78-30-34
    Average 96 stars, based on 1 article reviews
    presynaptic structure - by Bioz Stars, 2026-10
    96/100 stars
      Buy from Supplier

    96
    Bio-Rad rat anti cd68
    Rat Anti Cd68, supplied by Bio-Rad, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/cd68/Rat+anti+Mouse+CD68/pm42864910-175-49-51
    Average 96 stars, based on 1 article reviews
    rat anti cd68 - by Bioz Stars, 2026-10
    96/100 stars
      Buy from Supplier

    97
    Cell Signaling Technology Inc antibodies against cd68
    Macrophage-associated changes in medial collateral ligament (MCL) tissue after transplantation of ATG5-overexpressing MSCs. (A) Quantitative RT-PCR analysis of proinflammatory markers (CD80 and IL-12) and anti-inflammatory markers (CD163 and IL-10) in MCLs from aged rats on postoperative Day 14 after transplantation of MSC vector or MSC ATG5+ cells. (B) representative immunofluorescence images of <t>CD68</t> (red), CD86 (green) or CD206 (green), and DAPI (blue) in MCL sections from MSC vector and MSC ATG5+ groups (scale bar: 20 μm). (C) quantification of <t>CD68</t> + CD86 + and <t>CD68</t> + CD206 + macrophages in MCL tissue from MSC vector and MSC ATG5+ groups. (D) ELISA analysis of pro-inflammatory cytokines (TNF-α and IL-6) and anti-inflammatory cytokines (IL-4 and TGF-β1) in MCL tissues from MSC vector and MSC ATG5+ groups. Six rats in each subgroup. were used each experiment. all quantitative data are presented as mean ± SD. * p<0.05, ** p<0.01, *** p<0.001, and **** p<0.0001.
    Antibodies Against Cd68, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/cd68/CD68+Rabbit+mAb/pmc13656048-105-15-19
    Average 97 stars, based on 1 article reviews
    antibodies against cd68 - by Bioz Stars, 2026-10
    97/100 stars
      Buy from Supplier

    96
    Bio-Rad anti cd68
    Macrophage-associated changes in medial collateral ligament (MCL) tissue after transplantation of ATG5-overexpressing MSCs. (A) Quantitative RT-PCR analysis of proinflammatory markers (CD80 and IL-12) and anti-inflammatory markers (CD163 and IL-10) in MCLs from aged rats on postoperative Day 14 after transplantation of MSC vector or MSC ATG5+ cells. (B) representative immunofluorescence images of <t>CD68</t> (red), CD86 (green) or CD206 (green), and DAPI (blue) in MCL sections from MSC vector and MSC ATG5+ groups (scale bar: 20 μm). (C) quantification of <t>CD68</t> + CD86 + and <t>CD68</t> + CD206 + macrophages in MCL tissue from MSC vector and MSC ATG5+ groups. (D) ELISA analysis of pro-inflammatory cytokines (TNF-α and IL-6) and anti-inflammatory cytokines (IL-4 and TGF-β1) in MCL tissues from MSC vector and MSC ATG5+ groups. Six rats in each subgroup. were used each experiment. all quantitative data are presented as mean ± SD. * p<0.05, ** p<0.01, *** p<0.001, and **** p<0.0001.
    Anti Cd68, supplied by Bio-Rad, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/cd68/Rat+anti+Mouse+CD68/pm42863719-121-28-30
    Average 96 stars, based on 1 article reviews
    anti cd68 - by Bioz Stars, 2026-10
    96/100 stars
      Buy from Supplier

    Image Search Results


    Macrophage-associated changes in medial collateral ligament (MCL) tissue after transplantation of ATG5-overexpressing MSCs. (A) Quantitative RT-PCR analysis of proinflammatory markers (CD80 and IL-12) and anti-inflammatory markers (CD163 and IL-10) in MCLs from aged rats on postoperative Day 14 after transplantation of MSC vector or MSC ATG5+ cells. (B) representative immunofluorescence images of CD68 (red), CD86 (green) or CD206 (green), and DAPI (blue) in MCL sections from MSC vector and MSC ATG5+ groups (scale bar: 20 μm). (C) quantification of CD68 + CD86 + and CD68 + CD206 + macrophages in MCL tissue from MSC vector and MSC ATG5+ groups. (D) ELISA analysis of pro-inflammatory cytokines (TNF-α and IL-6) and anti-inflammatory cytokines (IL-4 and TGF-β1) in MCL tissues from MSC vector and MSC ATG5+ groups. Six rats in each subgroup. were used each experiment. all quantitative data are presented as mean ± SD. * p<0.05, ** p<0.01, *** p<0.001, and **** p<0.0001.

    Journal: Open Medicine

    Article Title: ATG5-overexpressing MSCs improve ligament healing with an associated shift toward M2 macrophage polarization in aged rats

    doi: 10.1515/med-2026-1545

    Figure Lengend Snippet: Macrophage-associated changes in medial collateral ligament (MCL) tissue after transplantation of ATG5-overexpressing MSCs. (A) Quantitative RT-PCR analysis of proinflammatory markers (CD80 and IL-12) and anti-inflammatory markers (CD163 and IL-10) in MCLs from aged rats on postoperative Day 14 after transplantation of MSC vector or MSC ATG5+ cells. (B) representative immunofluorescence images of CD68 (red), CD86 (green) or CD206 (green), and DAPI (blue) in MCL sections from MSC vector and MSC ATG5+ groups (scale bar: 20 μm). (C) quantification of CD68 + CD86 + and CD68 + CD206 + macrophages in MCL tissue from MSC vector and MSC ATG5+ groups. (D) ELISA analysis of pro-inflammatory cytokines (TNF-α and IL-6) and anti-inflammatory cytokines (IL-4 and TGF-β1) in MCL tissues from MSC vector and MSC ATG5+ groups. Six rats in each subgroup. were used each experiment. all quantitative data are presented as mean ± SD. * p<0.05, ** p<0.01, *** p<0.001, and **** p<0.0001.

    Article Snippet: After blocking with 5 % BSA, the sections were incubated overnight at 4 °C with antibodies against CD68 (1:200, CST, Cat# 97778), CD86 (1:100, Thermo Scientific, Cat# RAB02398 ), and CD206 (1:400, CST, Cat# 24595).

    Techniques: Tissue, Transplantation Assay, Quantitative RT-PCR, Analysis, Plasmid Preparation, Immunofluorescence, Enzyme-linked Immunosorbent Assay